Personal Data
Present address: Institute of Pharmaceutics, School of Pharmaceutical
science, Shandong University, 44 West Wenhua Rd. Jinan, Shandong, P. R. China, 250012
Tel: +86-0531-88382007 Fax : 0531-88382548
E-mail: yuxialuan@sdu.edu.cn
Education
09/1999-06/2004 Key Lab for Colloid and Interface Chemistry (Shandong University), Ministry of Education, Dr. degree,
09/1995-07/1999 College of Chemistry, Shandong Normal University, B.S. degree
Research Experience
09/2004-present School of Pharmaceutical Science, Shandong University
09/2006-09/2007 Department of Physics, E22, Technische Universität München, 85747 München, Germany, Posdoc.
09/2005-09/2006 Laboratoire des Colloïdes, Verres et Nanométeriaux (LCVN) UMR CNRS-UM2 nº 5587, Université Montellier II, Researcher assistant
Research Interest
¨ Properties and aggregation behavior of drug/surfactant catanionic vesicle;
¨ Synthesis, properties and application of small amphiphilic prodrug molecules;
¨ Synthesis, property and application of biodegradable copolymer;
Awards
2015 Excellent Master Thesis Direction Award of Shandong University
2013 Excellent Master Thesis Direction Award of Shandong University
2012 Third Prize for the Youth Teacher Teaching Competition in Pharmaceutical College
2011 The Youth Pharmaceutical Award of Chinese Pharmaceutical Association
2010 Excellent Bachelor Thesis Direction Award of Shandong Province
Research Foundation
1. The construction, property and sustained release of the self-assembly from the drug-based amphiphilic molecule, National Natural Science Foundation of China (No. 21373126)，2014.01-2017.12, 810,000;
2. Study on the structural vesicular membrane induced by the negative polyelectrolyte, National Natural Science Foundation of China (No. 20803044)，2009.01-2011.12, 190,000.
Papers Published in 5 years
24. Pei Zhang, Huiyuan Zhang, Wenxiu He, Dujuan Zhao, Aixin Song, Yuxia Luan*, Disulfide-linked amphiphilic polymer-docetaxel conjugates assembled redox-sensitive micelles for efficient anti-tumor drug delivery, Biomacromolecules, 2016, 17 (5), 1621-1632. （IF：5.75）
23. Jing Liu1, Jing Liu1, Dujuan Zhao, Naxin Ma, Yuxia Luan*, Highly enhanced leukemia therapy and oral bioavailability from a novel amphiphilic prodrug of cytarabine, RSC Advances, 2016, 6, 35991 - 35999. （IF：3.84 ）
22. Nuannuan Li1, Chunzhi Huang1, Yuxia Luan*, Aixin Song, Yunmei Song, Sanjay Garg, Active targeting co-delivery system based on pH-sensitive methoxy-poly(ethylene glycol)2K-poly(ε-caprolactone)4K-poly(glutamic acid)1K for enhanced cancer therapy, J. Colloid Interf. Sci. 2016, 472, 90-98. （IF：3.368）
21. Yuanyuan Guo, Pei Zhang, Qingyun Zhao, Kaiming Wang, Yuxia Luan*, Reduction-sensitive polymeric micelles based on docetaxel-polymer conjugates via disulfide linker for efficient cancer therapy, Macromolecular Bioscience, 2016, 16, 420-431. （IF：3.851）
20. Nuannuan Li, Lanxia Zhao, Lisi Qi, Zhonghao Li, Yuxia Luan* Polymer assembly: promising carriers as co-delivery systems for cancer therapy, Progress in Polymer Science, 2016, 58, 1-26. （IF：26.932 ）
19. Huiyuan Zhang, Kaiming Wang, Pei Zhang, Wenxiu He, Aixin Song, Yuxia Luan*, Redox-sensitive micelles assembled from amphiphilic mPEG-PCL-SS-DTX conjugates for the delivery of docetaxel, Colloids and Surfaces B: Biointerfaces, 2016, 142, 89-97. （IF：4.152）
18. Longlong Zhang, Pei Zhang, Qingyun Zhao, Yongchun Zhang, Longqiao Cao, Yuxia Luan* Doxorubicin-loaded polypeptide nanorods based on electrostatic interactions for cancer therapy, J. Colloid Interf. Sci. 2016, 464, 126-136. （IF：3.368 ）
17. Xiaoqing Ji, Chunhuan Shi, Nuannuan Li, Kaiming Wang, Zhonghao Li, Yuxia Luan* Catanionic drug-derivative nano-objects constructed by chlorambucil and its derivative for efficient leukaemia therapy, Colloids and Surfaces B: Biointerfaces, 2015, 136, 1081-1088. （IF：4.152）
16. Naxin Ma, Baohua Zhang, Jing Liu, Pei Zhang, Zhonghao Li, Yuxia Luan*,Green fabricated reduced graphene oxide: evaluation of its application as nano-carrier for pH-sensitive drug delivery, Int. J. Pharm., 2015, 496, 984-992. （IF：3.785）
15. Jing Liu, Naxin Ma, Dujuan Zhao, Zhonghao Li and Yuxia Luan*, Spiral assembly of amphiphilic cytarabine prodrug assisted by probe sonication: enhanced therapy index for leukemia, Colloids and Surfaces B: Biointerfaces, 2015, 136, 918-927. （IF：4.152）
14. Chunhuan Shi, Zhiqing Zhang, Jiaxing Shi, Fang Wang, Yuxia Luan*, Co-delivery of docetaxel and chloroquine via PEO-PPO-PCL/TPGS micelles for overcoming multidrug resistance, Int. J. Pharm., 2015, 495, 932-939. （IF：3.785）
13. Nuannuan Li, Pei Zhang, Chunzhi Huang, Yunmei Song, Sanjay Garg and Yuxia Luan* Co-delivery of doxorubicin hydrochloride and verapamil hydrochloride by pH-sensitive polymersomes for the reversal of multidrug resistance, RSC Advances, 2015, 5， 77986-77995. （IF：3.84 ）
12. Chunhuan Shi, Zhiqing Zhang, Fang Wang, Xiaoqing Ji, Zhongxi Zhao, Yuxia Luan*, Docetaxel-loaded PEO–PPO–PCL/TPGS mixed micelles for overcoming multidrug resistance and enhancing antitumor efficacy, J. Mater. Chem. B, 2015, 3, 4259-4271. （IF：6.626）
11. Feifei Li, Jing Liu, Jiaxing Shi, Yuxia Luan*, Synthesis and biological evaluation of a fatty acyl di-cytarabine prodrug, RSC. Advances, 2015, 5, 25382-25388. （IF：3.708 ）
10. Lisi Qi, Yuanyuan Guo, Jingjing Luan, Dianrui Zhang, Zhongxi Zhao, Yuxia Luan*, Folate-modified bexarotene-loaded bovine serum albumin nanoparticles as a promising tumor-targeting delivery system, J. Mater. Chem. B, 2014, 2 (47), 8361 - 8371. （IF：6.626）
9. Jing Liu, Yue Jiang, Yuting Cui, Chuanshan Xu, Xiaoqing Ji, Yuxia Luan*, Cytarabine-AOT catanionic vesicle-loaded biodegradable thermosensitive hydrogel as an efficient cytarabine delivery system, Int. J. Pharm., 2014, 473, 1-2, 560-571. （IF：3.785）
8. Xiaoqing Ji, Chunhuan Shi, Lisi Qi, Yuanyuan Guo, Nuannuan Li, Yuxia Luan* Preparation, properties and in vivo pharmacokinetic study of drug vesicles composed of diphenhydramine and AOT, RSC. Advances, 2014, 4 (107), 62698 - 62707. （IF：3.708 ）
7. Lanxia Zhao, Nuannuan Li, Kaiming Wang, Chunhuan Shi, Longlong Zhang and Yuxia Luan*, A Review of Polypeptide-based Polymersomes, Biomaterials, 2014, 35 (4), 1284-1301. （IF：8.312）
6. Longlong Zhang, Jing Liu, Tingting Tian, Xiaoqing Ji, Zhonghao Li and Yuxia Luan*, Pharmaceutically active ionic liquid self-assembled vesicles for application as an efficient drug delivery system, ChemPhysChem, 2013, 14 (15), 3454-3457.（IF：3.36）
5. Lanxia Zhao, Jing Liu, Longlong Zhang, Ya Gao, Zhiqing Zhang, Yuxia Luan*，Self-assembly properties, aggregation behavior and prospective application for sustained drug delivery of a drug-participating catanionic system，Int. J. Pharm., 2013, 452, 1-2, 108-115. （IF：3.785）
4. Jianmei Pang, Lanxia Zhao, Longlong Zhang, Zhonghao Li, Yuxia Luan*, Folate-Conjugated Hybrid SBA-15 Particles for Targeted Anticancer Drug Delivery, J. Colloid Interf. Sci. 2013, 395, 31-39. （IF：3.552）
3. Yue Jiang, Feifei Li, Yuxia Luan,* Wenting Cao, Xiaoqing Ji, Lanxia Zhao, Longlong Zhang, Zhonghao Li, Formation of drug/surfactant catanionic vesicles and their application in sustained drug release, Int. J. Pharm., 2012, 436, 1-2, 806-814. （IF：3.785）
2. Xiaoqing Cai, Yuxia Luan,* Aixin Song, Wei Shao, Zhonghao Li, Zhongxi Zhao, Huperzine A-phospholipid complex-loaded biodegradable thermosensitive polymer gel for controlled drug release, Int. J. Pharm., 2012, 433, 1-2, 102-111. （IF：3.785）
1. Yue Jiang, Yuxia Luan*, Fei Qin, Lanxia Zhao, and Zhonghao Li, Catanionic Vesicles from an Amphiphilic Prodrug Molecule: a New Concept of Drug Delivery System, RSC. Advances, 2012, 2(17), 6905-6912. （IF：3.708 ）
