Cheng Aixia, Ph.D, Professor

ADDRESS:
School of Pharmaceutical Sciences
Shandong University
No.44, Wenhuaxi Road, Jinan, 250012
P.R.China
Tel: 0086-531-88382012

Fax: 0086-531-88382019
E-mail:  aixiacheng@sdu.edu.cn

EDUCATION:
1999--2004: Doctor Degree Student in School of life Sciences, Shandong University

1995--1999: Undergraduate Student in the School of life Sciences, Ludong University

PROFESSIOAN EXPERIENCE:
2015-present: Professor of School of Pharmaceutical Sciences, Shandong University.
2006-2015: Associate professor of School of Pharmaceutical Sciences, Shandong University.

2011--2012:Visiting scholar of Brookhaven National Lab of USA.

2004--2006: Postdoctoral research in Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences

RESEARCH INTERESTS:
Biosynthesis and metabolic engineering of the plant secondary metablics

Tissue culture of medicinal plants

RESEARCH FOUNDING:

1.         Functional characterization and metabolic engineering of the key genes in bis(bibenzyl) biosynthesis pathway of the liverworts. Supported by the National Natural Science Foundation of China (No. 31170280), 2012.01-2015.12.

2.         Mechanism investigation of bHLH transcription factor on the bisbibenzyls and flavonoids biosynthesis in Plagiochasma appendiculatum. Supported by the National Natural Science Foundation of China (No.  31370330), 2014.01-2017.12.

RECENT PUBLICATION:

1.         Zhang YY, Xu RX, Gao S, Cheng AX* (2016) Enzymatic production of oroxylin A and hispidulin using a liverwort flavone 6-O-methyltransferase. FEBS Lett. 590, 2619–2628.

2.         Xu RX, Gao S, ZhaoY, Lou HX, Cheng AX* (2016) Functional characterization of a Mg²⁺-dependent O-methyltransferase with coumarin as preferred substrate from the liverwort Plagiochasma appendiculatum. Plant physiol. biochem. 106, 269-277.

3.         Xu RX, Zhao Y, Gao S, Zhang YY, Li DD, Lou HX, Cheng AX* (2015) Functional   characterization of a plastidal cation-dependent O-methyltransferase from the liverwort Plagiochasma appendiculatum. Phytochemistry 118, 33–41.

4.         Gao S, Yu HN, Xu RX, Cheng AX*, Lou HX* (2015). Cloning and functional characterization of a 4-coumarate CoA ligase from liverwort Plagiochasma appendiculatum. Phytochemistry 111, 48–58.

5.         Yu HN, Wang L, Sun B, Gao S, Cheng AX*, Lou HX* (2015). Functional characterization of a chalcone synthase from the liverwort Plagiochasma appendiculatum. Plant Cell Rep 34, 233–245.

6.         Han XJ, Wu YF, Gao S, Yu HN, Xu RX, Lou HX*, Cheng AX* (2014). Functional characterization of a Plagiochasma appendiculatum flavone synthase I showing flavanone 2-hydroxylase activity. FEBS Lett. 588, 2307-14.

7.         Yu HN, Liu XY, Gao S, Han XJ, Cheng AX*, Lou HX* (2014). Molecular cloning and functional characterization of a phenylalanine ammonia-lyase from liverwort Plagiochasma appendiculatum. Plant Cell Tiss Organ Cult 117, 265-277.

8.         Cheng AX, Gou JY, Yu XH,Yang HJ, Fang X, Chen XY, Liu CJ* (2013). Characterization and Ectopic Expression of a Populus Hydroxyacid Hydroxycinnamoyltransferase. Molecular Plant 1889-1903.

9.         Wu YF, Cai YH, Sun Y, Xu RX, Yu HN, Han XJ, Lou HX, Cheng AX* (2013). A single amino acid determines the catalytic efficiency of two alkenal double bond reductases produced by the liverwort Plagiochasma appendiculatum. FEBS Lett. 587, 3122-3128.

10.     Sun Y, Wu YF, Zhao Y, Han XJ, Lou HX, Cheng AX* (2013). Molecular cloning and biochemical characterization of two cinnamyl alcohol dehydrogenases from a liverwort Plagiochasma appendiculatum. Plant physiol biochem 70, 133-141.

* Corresponding author